I-CLEEN study

Investigating the effect of improving the cleaning of shared medical equipment on multi-resistant organisms in an intensive care unit: A quasi-experimental study (I-CLEEN)

About this study

This study uses the same intervention as the CLEEN study, but the setting for this study is intensive care. We encourage to you read about this CLEEN study first.

In the I-CLEEN study we are also exploring:

  • the potential transmission pathways of pathogens (MRSA, VRE, MRGNs) using whole genomic sequencing
    • All patients in the ICU are screened for pathogens (e.g. admission, discharge).
    • Equipment in the ICU will be regularly swabbed
  • exploring the experience of environmental cleaning staff (PSAs) in being part of the trial and how they would like to receive feedback about cleaning effectiveness.
    • We will undertake focus groups of PSAs

Study outcomes

Primary Outcome:

  • To evaluate the efficacy in additional cleaning of shared equipment in reducing healthcare-acquired infection (HAI) compared with normal practice in an adult intensive care unit (ICU)

Secondary outcomes

  • Determine the effect of audit and feedback on cleaning adherence of share hospital equipment
  • Describe the emergence of MRO transmission chains using whole-genome sequencing of patient and environmental isolates
  • Determine the experience of PSAs involved in the trial and determine preferences for receiving feedback on cleaning activity.